Mainstay Suites Odessa I-20

The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Being away from home does not mean you have to be out of balance at the non-smoking MainStay Suites Odessa I-20 hotel in Odessa, TX near Commanche Trail as well as the Medical Center Health System Hospital. Our location off Highway 385 offers easy access to attractions like McKinney Park, Ector County Coliseum and Globe of the Great Southwest. Invite your friends, family and colleagues to your next event in our meeting room, get work done in our business center and enjoy amenities like free hot breakfast, free WiFi, free parking and guest laundry services. Room amenities include a fully-equipped kitchen, dishwasher, microwave, refrigerator, desk and 42-inch TV. Earn rewards with every stay with our Choice Privileges Rewards program.